5 ọgwụgwọ PCOS dị mma

Mmụta Ahụike

Polycystic ovary syndrome, nke a na-akpọkarị PCOS, bụ nsogbu mgbagwoju anya nke hormonal nke na-emetụta ihe dịka 6-12% nke ụmụ nwanyị nọ na United States n'oge afọ ọmụmụ ha. Ọ bụkwa otu n'ime ihe ndị kachasị kpatara infertility, dị ka Lọ Ọrụ Maka Nchịkwa na Mgbochi Ọrịa (CDC), mana ọ bụ ihe kpatara bụ amaghị nke ọma. Nke ahụ na-eme ka o sie ike ịchọpụta ihe kacha mma PCOS ọgwụgwọ.

Kedu ihe mgbaàmà nke PCOS?

N'ihi adịghị mma nke ogo hormone dị na ovaries, ihe ngosipụta nke PCOS gụnyere oge ezughị oke ma ọ bụ oge ezighi ezi, oge ịhụ nsọ siri ike, na / ma ọ bụ enweghị ike ịhapụ akwa (ma ọ bụ ịmụ nwa). Oge ezumike nke a na-egbochi nwere ike ibute mgbaàmà ndị ọzọ na mmetụta ndị ọzọ, dị ka cysts na ovaries. Ozokwa, oburu na nwanyi nwere PCOS nwere otutu nwoke na androgen, aru ya nwere ike imeghachi omume site na itolite aru na ntutu nke iru, ya na ikekwe ihunanya otutu nwoke na nwoke. Uru ibu ibu bụkwa ihe ịrịba ama nke PCOS.

PCOS abụghị ihe egwu ndụ, mana ọ nwere ike ime ka ndụ na-akpasu iwe, ka ọ na-ekwu Shweta Patel, MD , onye OB / GYN na Orlando Health Dibịa Associates na Orlando, Florida. O nwere ike ibute ụfọdụ mgbaàmà ndị anaghị adị mma ma pụta ìhè ma mee ka windo ovula gị bụrụ ebumnuche na-agagharị, si otú ahụ na-eme ka o sie ike karịa-ma ọ gaghị ekwe omume-ịtụrụ ime n'oge kwesịrị ekwesị.

Gịnị na-akpata PCOS?

Ihe ruru nde ụmụ nwanyị ise na-arịa ọrịa polycystic ovarian syndrome, mana ọ bụ ndị amachaghị ihe kpatara ya. Ihe ole na ole na-akpata nsogbu gụnyere:

• mkpụrụ ndụ ihe nketa
• oke ibu
• insulin dị elu (protein nke na-enyere aka ịhazi ogo shuga shuga)
• elu androgen etoju

A 2018 ọmụmụ bipụtara na ntanetị na International Journal of Environmental Research na Ahụike Ọha kwubiri na agbụrụ ma ọ bụ ọnọdụ ala adịghị arụ ọrụ na PCOS.

Enwere ọnọdụ ndị ọzọ metụtara PCOS?

Otú ọ dị, nchọpụta na-egosi na ọtụtụ ọnọdụ ahụ ike metụtara ọrịa a — ọ bụ ezie na amatabeghị ma PCOS na-akpata nsogbu ndị a ma ọ bụ na nke ọzọ. Ihe Ọfịs na Ahụike Womenmụ nwanyị (nke Ngalaba Na-ahụ Maka Ahụ Ike na Ọrụ Ndị Ọrụ na United States na-agba) na-edepụta nsogbu ahụike isii dị ogologo metụtara PCOS:

• Ọrịa shuga: Ihe karịrị 50% nke ụmụ nwanyị achọpụtara na PCOS na-arịa ọrịa shuga ma ọ bụ ọrịa shuga tupu afọ 40, na-ekwu CDC .
• Ọbara mgbali elu: Womenmụ nwanyị nwere PCOS nọ na ihe egwu ahụike na-arị elu nke ọbara mgbali elu, nke nwere ike ibute ọrịa obi.
• Hypercholesterolemia: Mụ nwanyị nwere PCOS nwere ike inwe ọkwa LDL (ọjọọ) cholesterol ma e jiri ya tụnyere ụmụ nwanyị na-enweghị PCOS.
• Apneara ụra: Womenmụ nwanyị ndị nwere PCOS nọ n'ọnọdụ dị elu karịa ịmalite ọrịa ọgbụgba ume a, bụ nke iku ume oge na-akwụsịtụ ihi ụra. Ọnọdụ a nwere ike ibute ọrịa obi na ọrịa shuga.
• Da mba na nchegbu: Nyochaa nyocha 2016 na nyocha meta nke edepụtara na akwụkwọ akụkọ ahụ Ọrịa Neuropsychiatric na Ọgwụgwọ achọpụta na ụmụ nwanyị nwere PCOS nwere ihe dịka okpukpu atọ nwere ike ịnata ụjọ ma e jiri ya tụnyere ụmụ nwanyị na-enweghị PCOS. Nsonaazụ ahụ yiri nke ahụ maka ndị a chọpụtara na PCOS na mgbaàmà mgbaka.
• Ọrịa endometrium: Ihe omumu ndi mmadu bi na 2018 nke edeputara na akwukwo Ọgwụ kwubiri na umuaka ndi nwere PCOS nwere onodu onu ogugu di egwu nke oria cancer nke akpanwa.

Enwere PCOS gwọọ?

PCOS na-abụkarị nsogbu nke enwere ike ijikwa kama ịgwọ ya ebe ọ na-alaghachi azụ, ọkachasị ma ọ bụrụ na onye ọrịa ahụ enweta (ma ọ bụ nwetaghachi) ibu ahụ yana / ma ọ bụ achọpụta na ọ nwere ọrịa shuga, na-akọwa Jessica Onye ọzụzụ atụrụ, MD , OB / GYN nwere Minimally Invasive Gynecology na Baylor University Medical Center dị na Dallas, Texas. Ebe ọ bụ na mgbaàmà dị iche iche, Dr. Patel na-agbakwụnye na ọ na-eme ka ọgwụgwọ dị iche na ihe mgbaru ọsọ nke onye ọrịa.

Kedụ ka esi agwọ PCOS?

Nwere ike ịgwọ PCOS na nchikota nke mgbanwe ndụ na usoro ndị a. Lee usoro ọgwụgwọ PCOS ise ị nwere ike ịtụle.

1. Nri

Dr. Shepherd na-ekwu na ịgbanwe ụdị nri gị (ikekwe na atụmatụ dị ala) ga-enyere aka ịkwụsị pound na-achọghị. N'ọnọdụ ụfọdụ, nhalata ibu nwere ike ime ka insulin nwee mmetụta siri ike, na-arụ ọrụ nsọ, ma bulie ọmụmụ. Ọzọkwa, mgbanwe nri nwere ike inye aka na mgbochi insulin ma belata ohere ọ ga-abụ okwu metabolic, nke nwere ike ibute ọrịa shuga, hypercholesterolemia, ma ọ bụ ọbara mgbali elu, ọ gara n'ihu.

2. Njikwa ọmụmụ nwa

Maka ụmụ nwanyị na-anaghị achọ ịtụrụ ime, ọgwụ mgbochi ime ọnụ nwere ike inye aka ịhazi oge ma nyekwa estrogen cyclic, nke a na-akụkarị, Dr. Shepherd na-ekwu. Otu ọkachamara n'ọrịa ụmụ nwanyị nwere ike ịkọwa mkpụrụ ọgwụ mgbochi ịmụ nwa ma ọ bụ ụdị mgbochi ndị ọzọ nwere ma estrogen na progestin (dịka mgbanaka hormonal) iji belata ọbara ọgbụgba, belata oke ntutu isi, belata ihe otutu, ma belata ihe egwu nke ọrịa kansa endometrial.

3. Metformin

E gosipụtara Metformin [ọgwụ na-egbochi ọria mamịrị] iji mee ka ọ maliteghachi nkịtị, usoro ọmụmụ nsọ nwanyị nke nwanyị na 40-90% nke ndị ọrịa mụọ, Dr. Shepherd na-ekwu. Ọ na-agbakwụnye na ọgwụ ọgwụ a nwekwara ike melite njikọta spam na afọ ime n'ime ụmụ nwanyị nwere PCOS,ọ bụ ezie na ọ bụ ojiji maka nke a na-egosi na-ewere anya-labelụ na-ekwurịta banyere dọkịta gị. Ntinye onu nke ndi ogwu a na-akpo biguanides, metformin Ezubere iji mee ka mmeghachi ahụ nke insulin dịkwuo elu iji dozie ogo glucose na ndị mmadụ nwere ọrịa shuga 2. A 2015 ọmụmụ bipụtara na magazin Ọrịa shuga achọpụta na ọgwụ a nwekwara ike belata ọkwa LDL cholesterol. Ọkpụkpụ glucose bụ aha ama ama ama nke metformin.

Njikọ: Metformin maka ọgwụgwọ na-enweghị aha nke PCOS

4. Ọgwụ mgbochi androgen

Typedị usoro ọgwụgwọ eji egbochi androgens (aka nwoke homonụ mmekọahụ gụnyere testosterone), ọgwụ ndị a nwere ike inyere aka belata njiri mara nwoke ọ bụla metụtara PCOS, dịka acne, ntutu achọghị, na ntutu ntutu na-ala azụ. Inwe oke androgens nwekwara ike mezuo site na iji spironolactone [diuretic nke a na-enyekarị maka ịgwọ ọbara mgbali elu nke nwere mmetụta anti-androgenic], ma ọ bụ n'onwe ya ma ọ bụ yana ọgwụ ọgwụ mgbochi ịmụ nwa, Dr. Patel na-ekwu. Dr. Shepherd na-agbakwụnye na ibelata ọrụ testosterone nwere ike belata hirsutism [ụdị ntutu nwoke na ụmụ nwanyị] site na 40%. Ọfịs na Ahụike Womenmụ nwanyị dọrọ aka na ntị na klaasị ọgwụ ndị a nwere ike ibute nsogbu n'oge afọ ime. Nwekwara ike ịjụ ọkachamara n’ihe banyere ụwa gị banyere Vaniqa, nke bụ ude isi na-ewepụ ntutu.

5. Estrogen modulator

Iji mesoo infertility, Dr. Patel na-ekwu na ndị dọkịta na-ekwukarị ọgwụ na-emepụta etrogen, dị ka clomiphene citrate — ọgwụ ọnụ nke a na-akpọkarị Clomid, nke so n’otu ụdị ọgwụ ndị a na-akpọ ọgwụ ndị na-eme ka mkpụrụ ndụ na-akpali akpali. Ọ na - arụ ọrụ dịka estrogen site na ịgba ndị ovaries ume ịzụlite na ịhapụ akwa. Ederede 2015 nke edepụtara na akwụkwọ akụkọ ahụ Icslọọgwụ kọrọ na ndị inyom nwere PCOS bụ ndị jiri clomiphene citrate dị ka usoro ọgwụgwọ ọgwụ mbụ maka infertility nwere ọnụego afọ 70%.